BDBM50553483 CHEMBL4756595::US20230416221, Compound BAY1251152
SMILES COc1cc(F)ccc1-c1cc(Nc2cc(CS(C)(=N)=O)ccn2)ncc1F
InChI Key InChIKey=YZCUMZWULWOUMD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50553483
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9 [L156F](Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 1.25E+3nMAssay Description:The DMSO diluted compounds and the control compounds Dinaciclib, JSH-009, BAY-1211152, AZD4573 (all purchased from MCE, China) were mixed with the de...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 12.3nMAssay Description:The DMSO diluted compounds and the control compounds Dinaciclib, JSH-009, BAY-1211152, AZD4573 (all purchased from MCE, China) were mixed with the de...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Hefei Institutes of Physical Science, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair