BDBM50553493 CHEMBL4752000
SMILES CS(=N)(=N)Cc1cc2Nc3ncc(F)c(n3)-c3cccc(F)c3OCCCCOc(c1)c2
InChI Key InChIKey=DBOXIXXMMCQDIQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50553493
Affinity DataIC50: 3.40nMAssay Description:Inhibition of His-tagged human CDK9/cyclin T1 expressed in insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.52E+3nMAssay Description:Inhibition of His-tagged human CDK2 (M1 to L298 residue)/cyclin E1 (M1 to A395 residue) expressed in sf9 insect cells using biotin Ttds-YISPLKSPYKISE...More data for this Ligand-Target Pair
