BDBM50553505 CHEMBL4741959

SMILES CNC(=O)c1nc(C)n2ccc(Nc3nccc(n3)-n3cc(N[C@@H]4CCOC[C@@H]4N)c(C)n3)cc12

InChI Key InChIKey=NPSUYJDNOFYGMK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553505   

TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553505(CHEMBL4741959)Copy SMILESCopy InChI

Affinity DataIC50: 3.20nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553505(CHEMBL4741959)Copy SMILESCopy InChI

Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL