BDBM50553507 CHEMBL4748041

SMILES CNC(=O)c1nn(C)c2ccc(Nc3nccc(n3)-n3cc(NCC4(N)CC4)c(C)n3)cc12

InChI Key InChIKey=ACAIBIBNIFXKCV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553507   

TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553507(CHEMBL4748041)Copy SMILESCopy InChI

Affinity DataIC50: 0.340nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553507(CHEMBL4748041)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL