BDBM50553508 CHEMBL4797815

SMILES Cc1nn(cc1N[C@@H]1CCOC[C@@H]1N)-c1ccnc(Nc2ccc3n(C)cc(C(=O)C(F)(F)F)c3c2)n1

InChI Key InChIKey=QKVTVPBQFHJNPR-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553508   

TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553508(CHEMBL4797815)Copy SMILESCopy InChI

Affinity DataIC50: 0.220nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50553508(CHEMBL4797815)Copy SMILESCopy InChI

Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL