BDBM50553678 CHEMBL4789524

SMILES CN(C)C(=O)c1ccc(Oc2nc(nc(n2)-c2cnc(N)nc2)N2CCOCC2)cc1

InChI Key InChIKey=PDGYXVSGGSRTIY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553678   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sphaera Pharma

Curated by ChEMBL

LigandBDBM50553678(CHEMBL4789524)Copy SMILESCopy InChI

Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
Sphaera Pharma

Curated by ChEMBL

LigandBDBM50553678(CHEMBL4789524)Copy SMILESCopy InChI

Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL