BDBM50554071 CHEMBL4758548

SMILES CCn1nc(cc1Nc1nc(cs1)-c1ccc(c(OC)c1)-n1cnc(C)c1)C(C)(C)C

InChI Key InChIKey=MREQDPIDUGPKBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554071   

TargetPresenilin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50554071(CHEMBL4758548)
Affinity DataIC50: 96nMAssay Description:Modulation of gamma secretase in human SH-SY5Y cells overexpressing wild type APP751 assessed as inhibition of amyloid beta (35 to 42 residues) forma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed