BDBM50554257 CHEMBL4742990

SMILES COc1cccc(Cn2cnc3ccc(cc3c2=O)-c2cn[nH]c2)c1

InChI Key InChIKey=QQJKCGXOHWHBQV-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50554257   

TargetBeta-adrenergic receptor kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GRK2 by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 11nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 246nMAssay Description:Inhibition of human ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 483nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human PKBalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 6(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of human GRK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of human CaMK2betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human GRK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 9.07E+3nMAssay Description:Inhibition of human PKCbeta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 9.14E+3nMAssay Description:Inhibition of human GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed