BDBM50554286 CHEMBL4798424

SMILES CSCC[C@H](NC(=O)[C@H](C)NC(=O)CN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(N)=O

InChI Key InChIKey=KTFSNAJLHRKGRR-PLWNBHSFSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554286   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Tokyo Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50554286(CHEMBL4798424)
Affinity DataKd:  4.36E+5nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant in presence of 50 uM p53 peptide by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Tokyo Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50554286(CHEMBL4798424)
Affinity DataKd:  1.95E+5nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed