BDBM50555890 CHEMBL4751542

SMILES Nc1ccc2CCS(=O)(=O)N(CCCCN3CCN(CC3)c3cccc4sccc34)c2c1

InChI Key InChIKey=MDHWQDYGWGZBFM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50555890   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50555890(CHEMBL4751542)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) preincubated for 60 mins followed by addition of Eu-cAMP and measured after 60 mins by plate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50555890(CHEMBL4751542)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) assessed as decrease in intracellular calcium flux preincubated with calcium followed by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50555890(CHEMBL4751542)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at D2 receptor (unknown origin) preincubated for 60 mins followed by addition of Eu-cAMP and measured after 60 mins by plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed