BDBM50556068 CHEMBL4783159

SMILES O=C1c2nnn(c2C(=O)c2ccccc12)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=CVBWHHKUUGWTMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556068   

TargetTryptophan 2,3-dioxygenase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50556068(CHEMBL4783159)
Affinity DataIC50: 42nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins microplate s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50556068(CHEMBL4783159)
Affinity DataIC50: 45nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed