BDBM50556134 CHEMBL4746282

SMILES Clc1ccc2c(c1)oc1ccc(OCCCCCCN3CCCCCC3)cc1c2=O

InChI Key InChIKey=ZWCILIRMPOCMLE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556134   

TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50556134(CHEMBL4746282)
Affinity DataIC50: 235nMAssay Description:Inhibition of Electric eel AChE using ATCI as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50556134(CHEMBL4746282)
Affinity DataKi:  602nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50556134(CHEMBL4746282)
Affinity DataIC50: 975nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI cells using p-tyramine as substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50556134(CHEMBL4746282)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of equine serum BChE using BTCI as substrate incubated for 5 mins followed by substrate addition and measured after 5 mins by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed