BDBM50556281 CHEMBL4790545

SMILES COc1ccc2cc(ccc2c1)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=AIIWJMPOAUNFLG-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50556281   

TargetCholinesterase(Horse)
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataKi:  150nMAssay Description:Mixed type inhibition of equine serum BChE assessed as decrease in Vmax and increase in Km using varying level of S-butyrylthiocholine iodide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataKi:  210nMAssay Description:Non-competitive inhibition of recombinant human AChE assessed as decrease in Vmax with constant Km using varying level of acetylthiocholine iodide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50: 410nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50: 470nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed