BDBM50556346 CHEMBL4798638

SMILES OC(CNC1CCN(CCSC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=GHMRSCYBFHYOPJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50556346   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatal membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  88nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  701nMAssay Description:Displacement of [3H]-N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50556346(CHEMBL4798638)
Affinity DataKi:  2.67E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed