BDBM50556433 CHEMBL4752374

SMILES O=C(Nc1nc(c(s1)C(=O)c1ccc(cc1)-c1cccs1)-c1ccccc1)C1(CC1)c1ccc2OCOc2c1

InChI Key InChIKey=SIPLAMOJHJSNEZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556433   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50556433(CHEMBL4752374)
Affinity DataEC50:  1.06E+3nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed