BDBM50556681 CHEMBL4795804

SMILES Clc1cccc(c1)C(=O)Nc1c[nH]nc1-c1nc(c[nH]1)-c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=QIEUKJRYCZYZDC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556681   

TargetTyrosine-protein kinase JAK3(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK2 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50556681(CHEMBL4795804)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Aurora A (unknown origin) incubated for 40 mins in presence of ATP by Kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed