BDBM50557187 CHEMBL4763549::US12030867, Compound 4a

SMILES Cc1cc2cc(-n3nc(C)c4c3CC(C)(C)CC4=O)cc(N[C@H]3CC[C@H](O)CC3)c2c(=O)[nH]1

InChI Key InChIKey=REYVPGARPINGLW-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50557187   

TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557187BDBM50557187(CHEMBL4763549 | US12030867, Compound 4a)
Affinity DataKd:  101nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557187BDBM50557187(CHEMBL4763549 | US12030867, Compound 4a)
Affinity DataIC50: 101nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557187BDBM50557187(CHEMBL4763549 | US12030867, Compound 4a)
Affinity DataKd:  294nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557187BDBM50557187(CHEMBL4763549 | US12030867, Compound 4a)
Affinity DataIC50: 294nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed