BDBM50557192 CHEMBL4789323::US12030867, Compound 4f

SMILES Cc1nn(-c2cc(N[C@H]3CC[C@H](O)CC3)c3c(=O)[nH]c(C(C)(C)C)cc3c2)c2c1C(=O)CC(C)(C)C2

InChI Key InChIKey=NPIUOSXQRJZWKI-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50557192   

TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557192BDBM50557192(CHEMBL4789323 | US12030867, Compound 4f)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557192BDBM50557192(CHEMBL4789323 | US12030867, Compound 4f)
Affinity DataKd: >5.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame Du Lac

US Patent
LigandChemical structure of BindingDB Monomer ID 50557192BDBM50557192(CHEMBL4789323 | US12030867, Compound 4f)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557192BDBM50557192(CHEMBL4789323 | US12030867, Compound 4f)
Affinity DataKd: >5.00E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent