BDBM50557855 CHEMBL4740644

SMILES Clc1cccc(Nc2nn3c(Cc4ccc5OCOc5c4)nnc3s2)c1

InChI Key InChIKey=MTLOGVMDUHGJIH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557855   

TargetHepatocyte growth factor receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50557855(CHEMBL4740644)
Affinity DataKi:  80nMAssay Description:Inhibition of c-Met (unknown origin) using poly Glu-Tyr as substrate preincubated for 10 mins followed by ATP addition by phosphoenolpyruvate/pyruvat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50557855(CHEMBL4740644)
Affinity DataIC50: 300nMAssay Description:Inhibition of c-MET in human SNU-5 cells measured after 6 hrs by steady-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed