BDBM50557893 CHEMBL4763370

SMILES Cc1ccc(NC(=O)[C@H]2CC[C@H](Cn3c(=O)n(Cc4cccc(c4C#N)C(F)(F)F)c4cccc(C)c4c3=O)CC2)cn1

InChI Key InChIKey=HOSHPNDTAUJRNF-HZCBDIJESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557893   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557893(CHEMBL4763370)
Affinity DataIC50:  40nMAssay Description:Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557893(CHEMBL4763370)
Affinity DataIC50:  4nMAssay Description:Inhibition of human TNKS1 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed