BDBM50557898 CHEMBL4749857

SMILES COc1cccc2n(Cc3cccc(c3C#N)C(F)(F)F)c(=O)n(C[C@H]3CC[C@@H](CC3)C(O)=O)c(=O)c12

InChI Key InChIKey=OPXFUPAGTLOLPU-WKILWMFISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557898   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557898(CHEMBL4749857)
Affinity DataIC50:  126nMAssay Description:Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50557898(CHEMBL4749857)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of human TNKS1 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed