BDBM50558664 CHEMBL4752156

SMILES [H][C@@]12COP(S)(=O)O[C@@]3([H])[C@@H](F)[C@@H](O[C@]3([H])COP(S)(=O)O[C@@]1([H])C[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(O)ncnc12

InChI Key InChIKey=ZOHTYTWCUFTHSD-CBAZNMGYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50558664   

TargetStimulator of interferon genes protein(Mus musculus)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  4.70E+3nMAssay Description:Activation of STING in human blood assessed as induction of type I IFNs incubated for 18 to 20 hrs by QUANTI-Blue assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  9.90E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed