BDBM50558795 CHEMBL4789372

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)c1nc(CN(C)C)c(o1)-c1ccccc1

InChI Key InChIKey=JKPFXWCWKYDCSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558795   

TargetOrexin/Hypocretin receptor type 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50558795(CHEMBL4789372)
Affinity DataIC50: 557nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as inhibition of orexin A-induced intracellular Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50558795(CHEMBL4789372)
Affinity DataIC50: 983nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of orexin A-induced intracellular Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed