BDBM50558797 CHEMBL4797142

SMILES COC(=O)C1(C)CC1c1coc(n1)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=LCFNKEOIAZLRBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558797   

TargetOrexin receptor type 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50558797(CHEMBL4797142)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of orexin A-induced intracellular Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50558797(CHEMBL4797142)
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as inhibition of orexin A-induced intracellular Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed