BDBM50559857 CHEMBL4780840

SMILES CCCC(C)Nc1nc(N)nc2cccnc12

InChI Key InChIKey=PWJVWMXTULXVRU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559857   

TargetToll-like receptor 8(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50559857(CHEMBL4780840)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at TLR8 in human cryopreserved PBMC assessed as inhibition of IL-12p40 production measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50559857(CHEMBL4780840)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at TLR7 in human cryopreserved PBMC assessed as induction of IFNalpha production measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed