BDBM50559858 CHEMBL4740640

SMILES CCC[C@H](CO)Nc1nc(N)nc2cccnc12

InChI Key InChIKey=OXDCXEIDFKATID-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559858   

TargetToll-like receptor 8(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50559858(CHEMBL4740640)
Affinity DataEC50:  1.90E+4nMAssay Description:Agonist activity at TLR8 in human cryopreserved PBMC assessed as inhibition of IL-12p40 production measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50559858(CHEMBL4740640)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at TLR7 in human cryopreserved PBMC assessed as induction of IFNalpha production measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed