BDBM50560332 CHEMBL4782472

SMILES [H][C@]12CCC(=O)N1C[C@@H](CC2)c1nc(-c2ccc(cc2OC(F)(F)F)C(=O)Nc2cc(ccn2)C(F)(F)F)c2c(N)nccn12

InChI Key InChIKey=FHEGAOAKVDINAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560332   

TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50560332(CHEMBL4782472)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50560332(CHEMBL4782472)
Affinity DataIC50: 74nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in cell surface CD69 expression preincubated for 1 hr followed by stimulation with goat anti-hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed