BDBM50560703 CHEMBL1349996
SMILES CCN1\C(Sc2ccc(OC)cc12)=C/C(C)=O
InChI Key InChIKey=BGVLELSCIHASRV-NTUHNPAUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50560703
Affinity DataKi: 210nMAssay Description:Inhibition of full length wild type CLK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate additi...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nMAssay Description:Inhibition of recombinant CLK3 (unknown origin) using Ac-ERMRPRKRQGSVdP(Sox)G-NH2 as substrate after 5 mins by Omnia Kinase AssayMore data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to CLK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to PIM1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to PIM3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to CSNK1G2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to CSNK1G3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to CSNK1D (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to CSNK1E (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 19(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to MAP3K19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Inhibition of CLK1 (H148 to I484 residues) (unknown origin) at 15 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 7.78E+3nMAssay Description:Inhibition of CLK3 (R134 to T484 residues) (unknown origin) at 15 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to DYRK1B (unknown origin)More data for this Ligand-Target Pair