BDBM50560762 CHEMBL4762759

SMILES Cc1cc(Nc2ccc(C#N)c(c2)C#N)nc(n1)-c1ccccc1

InChI Key InChIKey=IJFNBSAYLVYVEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560762   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-University Bonn

Curated by ChEMBL
LigandPNGBDBM50560762(CHEMBL4762759)
Affinity DataIC50: 188nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells co-expressing GFP preincubated for 30 mins followed by Hoechst 33342 addition and measured every 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-University Bonn

Curated by ChEMBL
LigandPNGBDBM50560762(CHEMBL4762759)
Affinity DataIC50: 548nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells co-expressing GFP preincubated for 15 mins followed by pheophorbideA addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed