BDBM50560874 CHEMBL4752076

SMILES ONC(=O)c1ccc(CNCc2nnnn2Cc2ccccc2)cc1

InChI Key InChIKey=FVEJLNXIGDQJLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560874   

TargetHistone deacetylase 6(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560874(CHEMBL4752076)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant HDAC6 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50560874(CHEMBL4752076)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed