BDBM50560900 CHEMBL4777817

SMILES CC(C)c1ccn2ncnc(N[C@H]3CC[C@H](CC3)N3CCN(CC3)C(=O)CCC(=O)NCCCCCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)c12

InChI Key InChIKey=PDSUGWAIWCZKFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560900   

TargetInterleukin-1 receptor-associated kinase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560900(CHEMBL4777817)
Affinity DataIC50: 6nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50560900(CHEMBL4777817)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed