BDBM50561620 CHEMBL4744811

SMILES C[C@H]1CO[C@H](CN1CC[C@H]1CC[C@@H](CC1)NC(=O)c1cc2ccccc2[nH]1)c1ccc(N)nc1

InChI Key InChIKey=ADDKZOUNFAZVBP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50561620   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-(R)-(+)7-OH-DPAT from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cells after 90 mins by microbeta counting based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]-(R)-(+)7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from human D2L receptor expressed in HEK293 cells after 90 mins by microbeta counting based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi:  2.19E+4nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in HEK293 cells after 60 mins by microbeta counting based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50561620(CHEMBL4744811)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-SCH23390 from human D1 receptor expressed in HEK293 cells after 60 mins by microbeta counting based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed