BDBM50561821 CHEMBL4782804

SMILES C=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(NC(=O)c2cccc(n2)-c2ccn[nH]2)cc1

InChI Key InChIKey=WQVPGYMGERDXLH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50561821   

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant IRAK1 (unknown origin) by Invitrogen adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 19(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 57nMAssay Description:Inhibition of wild-type human partial length YSK4 (T1019 to H1328 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50561821(CHEMBL4782804)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using methylcoumarin-labeled peptide as substrate in presence of ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed