BDBM50561896 CHEMBL4790624

SMILES ONC(=O)c1ccc(CNC(=O)N2CCC3(CN(Cc4ccccc4)c4ccccc34)CC2)cc1

InChI Key InChIKey=SITOVBQRJFGXTE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50561896   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50561896(CHEMBL4790624)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50561896(CHEMBL4790624)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli using Fluor de Lys substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50561896(CHEMBL4790624)
Affinity DataIC50:  110nMAssay Description:Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed