BDBM50562307 CHEMBL4755061

SMILES CC(C)Oc1ccc(cc1-c1cn(C)c(=O)c2[nH]c(cc12)C(=O)NCCCCCCC(=O)NO)C(C)(C)O

InChI Key InChIKey=ZPZTZOURCDUBLM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50562307   

TargetHistone deacetylase 6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged BRD4 bromodomain 2 (unknown origin) using [Lys (5,8,12,16) Ac] H4(1-21) as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 30nMAssay Description:Inhibition of His-tagged BRD4 bromodomain 1 (unknown origin) using [Lys (5,8,12,16) Ac] H4(1-21) as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC3 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50562307(CHEMBL4755061)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed