BDBM50562355 CHEMBL4755913

SMILES Cl.Cl.CCCNC(=N)Nc1ccc(Cc2ccc(NC3=NCCN3)cc2)cc1

InChI Key InChIKey=FBXGXWMLTNKLSQ-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562355   

TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562355(CHEMBL4755913)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in human brain membrane by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562355(CHEMBL4755913)
Affinity DataEC50:  4.60E+4nMAssay Description:Agonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562355(CHEMBL4755913)
Affinity DataEC50:  4.87E+5nMAssay Description:Agonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as stimulation of [35S]GTPgammaS binding in presence of adrenergic a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562355(CHEMBL4755913)
Affinity DataEC50:  3.00E+4nMAssay Description:Antagonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as inhibition of UK14304-induced stimulation of [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed