BDBM50562885 CHEMBL4783641

SMILES ONC(=O)CCCCn1cc(COc2cc3ncnc(Nc4cccc(Cl)c4F)c3cc2NC(=O)C=C)nn1

InChI Key InChIKey=ATEKSUDRIVWTTK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50562885   

TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR L858R (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 16nMAssay Description:Inhibition of HER2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 17nMAssay Description:Inhibition of EGFR L858R/T790M (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 43nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562885(CHEMBL4783641)
Affinity DataIC50: 132nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed