BDBM50563275 CHEMBL4761013

SMILES ONC(=O)c1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1-c1ccccc1

InChI Key InChIKey=XYLVZKXNIYAIQC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50563275   

TargetHistone deacetylase 4(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human HDAC4 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-LGK(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Class 1 histone deacetylase in human THP-1 cells using Ac-LGK(Ac)-AMC as substrate incubated for 3 hrs followed by 50 uM SAHA addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human HDAC8 using Ac-LGK(TFA)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human HDAC9 using Ac-LGK(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human HDAC5 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed