BDBM50563810 CHEMBL4798255

SMILES CN(C)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(C)c4ccc(O)cc34)c2c1

InChI Key InChIKey=JNYJJXLTWZLGQH-IUXPMGMMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50563810   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50563810(CHEMBL4798255)
Affinity DataIC50:  93nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50563810(CHEMBL4798255)
Affinity DataIC50:  93nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50563810(CHEMBL4798255)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50563810(CHEMBL4798255)
Affinity DataIC50:  13nMAssay Description:Inhibition of TrkB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50563810(CHEMBL4798255)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed