BDBM50564451 CHEMBL4782796

SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(Br)ccc23)c1C

InChI Key InChIKey=WNDUJGBGBDASMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564451   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
University Of Colorado

US Patent
LigandPNGBDBM50564451(CHEMBL4782796 | US12435059, Compound 22)
Affinity DataIC50: 82.5nMAssay Description:LANCE® Eu time-resolved fluorescence resonance energy transfer (TR-FRET) kinase assays (PerkinElmer) were performed in 384-well OptiPlates (Corning) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
University Of Colorado

US Patent
LigandPNGBDBM50564451(CHEMBL4782796 | US12435059, Compound 22)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50564451(CHEMBL4782796 | US12435059, Compound 22)
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50564451(CHEMBL4782796 | US12435059, Compound 22)
Affinity DataIC50: 208nMAssay Description:LANCE® Eu time-resolved fluorescence resonance energy transfer (TR-FRET) kinase assays (PerkinElmer) were performed in 384-well OptiPlates (Corning) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent