BDBM50564455 CHEMBL4781062

SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(CCOC)cc23)c1C

InChI Key InChIKey=GRRWNPDZXOTJNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564455   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
University Of Colorado

US Patent
LigandPNGBDBM50564455(CHEMBL4781062 | US12435059, Compound 9)
Affinity DataIC50: 96.6nMAssay Description:LANCE® Eu time-resolved fluorescence resonance energy transfer (TR-FRET) kinase assays (PerkinElmer) were performed in 384-well OptiPlates (Corning) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
University Of Colorado

US Patent
LigandPNGBDBM50564455(CHEMBL4781062 | US12435059, Compound 9)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50564455(CHEMBL4781062 | US12435059, Compound 9)
Affinity DataIC50: 296nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50564455(CHEMBL4781062 | US12435059, Compound 9)
Affinity DataIC50: 296nMAssay Description:LANCE® Eu time-resolved fluorescence resonance energy transfer (TR-FRET) kinase assays (PerkinElmer) were performed in 384-well OptiPlates (Corning) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent