BDBM50564611 CHEMBL4788502
SMILES OC(c1cc(Nc2cc(Oc3cn(nc3C3CC(F)(F)C3)C3CC3)ccn2)ccn1)C(F)(F)F
InChI Key InChIKey=ZKDHGARURWAONW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50564611
Affinity DataIC50: 28nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK5 (unknown origin) measured after 120 mins of incubation by ADP-Glo kinase assayMore data for this Ligand-Target Pair