BDBM50564773 CHEMBL4797980

SMILES COc1ccc(cc1)-c1ccccc1N1CCN(C[C@@H](O)COc2ccc(cc2)-c2cn3ccccc3n2)CC1

InChI Key InChIKey=UMIUFZIZERXHBB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564773   

Target5-hydroxytryptamine receptor 7(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50564773(CHEMBL4797980)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand bind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50564773(CHEMBL4797980)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50564773(CHEMBL4797980)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed