BDBM50564995 CHEMBL4780183

SMILES CCCS(=O)(=O)Nc1cc(ccc1OC)-c1cc(cnc1N)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=KAEJEDBJAIIDDU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564995   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Houston

Curated by ChEMBL

LigandBDBM50564995(CHEMBL4780183)Copy SMILESCopy InChI

Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
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TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston

Curated by ChEMBL

LigandBDBM50564995(CHEMBL4780183)Copy SMILESCopy InChI

Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL