BDBM50565427 CHEMBL4784002

SMILES Cn1cc(cn1)-c1ccc2c(Nc3ccc(NC(=O)Nc4cccc(F)c4)cc3)ncnc2c1

InChI Key InChIKey=UXYIPHKBTFKDMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565427   

TargetAurora kinase B(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50565427(CHEMBL4784002)
Affinity DataIC50: 0.336nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50565427(CHEMBL4784002)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50565427(CHEMBL4784002)
Affinity DataIC50: 12nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed