BDBM50565596 CHEMBL4797870

SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(c2c(F)cccc12)S(=O)(=O)CCN1CCOCC1

InChI Key InChIKey=SUKAZYQBSGRSIV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50565596   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565596(CHEMBL4797870)
Affinity DataEC50:  0.690nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed