BDBM50565714 CHEMBL4787904

SMILES CCN(CC)CCCOc1cc2c(Oc3ccc(Nc4nccc5[nH]cc(-c6ccc(F)cc6)c(=O)c45)cc3F)ncnc2cc1OC

InChI Key InChIKey=DOGHUAAKQKSPCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565714   

TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50565714(CHEMBL4787904)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50565714(CHEMBL4787904)
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50565714(CHEMBL4787904)
Affinity DataIC50: 397nMAssay Description:Inhibition of MET in human MKN-45 cells assessed as reduction in HGF-mediated autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed