BDBM50565749 CHEMBL4794093

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2cccc(c2)C#Cc2cccc3[nH]nc(N)c23)cc(c1)C(F)(F)F

InChI Key InChIKey=ULSOOODMFMCIIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565749   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50565749(CHEMBL4794093)
Affinity DataIC50: 26nMAssay Description:Inhibition of wild type BCR-ABL (unknown origin) incubated for 40 mins in presence of [gamma33P]ATP by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50565749(CHEMBL4794093)
Affinity DataIC50: 824nMAssay Description:Inhibition of BCR-ABL T315I mutant (unknown origin) incubated for 40 mins in presence of [gamma33P]ATP by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed