BDBM50565751 CHEMBL4794284

SMILES Nc1n[nH]c2cccc(C#Cc3cccc(c3)C(=O)Nc3cc(CN4CCOCC4)cc(c3)C(F)(F)F)c12

InChI Key InChIKey=GYTPDENASJFHSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565751   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50565751(CHEMBL4794284)
Affinity DataIC50: 571nMAssay Description:Inhibition of wild type BCR-ABL (unknown origin) incubated for 40 mins in presence of [gamma33P]ATP by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50565751(CHEMBL4794284)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of BCR-ABL T315I mutant (unknown origin) incubated for 40 mins in presence of [gamma33P]ATP by scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed