BDBM50566254 CHEMBL4781656

SMILES COc1ccc(cc1)S(=O)(=O)c1cc(C(N)=O)c(NC(=O)C(C)(C)O)s1

InChI Key InChIKey=DNKIVLHKDMKSIA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566254   

LigandPNGBDBM50566254(CHEMBL4781656)
Affinity DataEC50:  20nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50566254(CHEMBL4781656)
Affinity DataEC50:  478nMAssay Description:Potentiation of CFTR G551D mutant (unknown origin) expressed in human HEK293 cells co-expressing YFP incubated for 10 mins by halide potentiator assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed